1. Cancer (Man vs Body)
The most evident conflict is most defiantly cancer. Though it is the common bond that brings the two together, it is also the beast that is killing Hazel. Her cancer is her curse that made her lungs hardly work and forcing her to carry her burdens every where she goes in the form of a oxygen tank on wheels. It also conflicts with Gus and Hazel's relationship, limiting their time together. I would categorize it as Man vs. Body, because it is a factor within herself she has no control over, unlike Man vs. Self.
2. Hazel (Man vs Self)
Near the end of this book, Hazel and Augustus experience a life-altering event (I don't want to give anything away). Through this reflective period of time, Hazel struggles to cope with herself and parts of her heart falling apart. As a reader, it was difficult to see the character who had risen from the ashes, to be so broken again. This really captures her for who she is, showing she is fragile and easily shaken by the walls around her.
3. Social Skills (Man vs Society)
Because of a past 3 year re-movement from a public schooling system, Hazel Grace has been socially withdrawn. This is very important to understand her at the beginning of the book. She has an unwillingness to see people, almost unknowing as to how to handle herself in a public environment and not good at talking to other people, with less than a handful of friends. People saw Hazel with her oxygen and short hair smiling, but frightened and judgmental. This is another reason why her relationship with Gus is so miraculous; her ability to openly connect to another person on that level and so immediately.